Next-Gen Sequencing

 

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Epigenome Sequencing
Introductions
Methylation of chromosomal DNA is a major regulatory pathway of gene expression. Aberrant DNA methylations are indication of various human diseases, including cancer. MACROGEN offers comprehensive portfolio of epigenome sequencing services, which includes experienced and customized bioinformatic analysis. To tailor to each research designs, we provide different methyl-sequencing methods, including Whole Genome Bisulfite Sequencing (WGBS), Reduced Representation Bisulfite Sequencing (RRBS), MBD (methyl-CpG binding protein) Capture Sequencing, and ChIP Sequencing.
Sequencing platform
• HiSeq2000/2500
• MiSeq system (Methylation / MBD, ChIP sequencing)
Data Analysis*
Standard data analysis
• Global Methylation Profiles
• Specific Methylation Profiles
- CpG Islands
- Differentially Methylation Regions(DMRs)
• Advanced data analysis
- DMR-Associated Genes
- Gene Set Analysis
- Comparative Analysis
*Data Analysis may vary depending on the avaliability of reference and the type of platform.
For any inquiry of NGS service, please feel free to contact us.
E-mail : ngs@macrogen.com